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Correspondence
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Volume 340:1288-1290 April 22, 1999 Number 16
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Prognostic Score for Hodgkin's Disease

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 by Morell, R. J.
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 by Hasenclever, D.
To the Editor: The prognostic scoring system for Hodgkin's disease proposed by Hasenclever and Diehl (Nov. 19 issue)1 has addressed a difficult challenge for clinicians. We wish to raise two issues of concern regarding this article. First, there was no histologic review, and it is uncertain whether cases of the nodular lymphocyte-predominant subtype were included. This form of Hodgkin's disease is different in both presentation and prognosis from the classic form of the disease. Only 3 percent of cases had lymphocyte-predominant Hodgkin's disease; distortion of the analysis would have been slight, but it would be incorrect to apply the conclusions . . . [Full Text of this Article]

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