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Previous Volume 340:149-150 January 14, 1999 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Cullen's sign, or periumbilical ecchymosis, is classically associated with hemorrhagic pancreatitis but may also occur with retroperitoneal hemorrhage, splenic rupture, ruptured ectopic pregnancy, and leaking aortic aneurysm.^1,2,3 In fact, any process causing hemoperitoneum may lead to diffusion of blood along fascial planes and cause ecchymosis in the periumbilical area or over the flanks (Turner's sign).¹ Cancer is not mentioned as a cause of Cullen's sign in a classic textbook on surgical physical diagnosis,¹ but the sign has been reported on rare occasions in association with lymphoma and hepatocellular carcinoma.^2,3 I describe the case of a patient with . . . [Full Text of this Article]

References

Related Letters:

Cullen's Sign in Metastatic Thyroid Cancer
Rosai J., Marinella M. A.
Extract | Full Text  
N Engl J Med 1999; 340:1767-1768, Jun 3, 1999. Correspondence

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• Sultan, A, Velaga, M R, Fleet, M, Cheetham, T (2006). Cullen's sign and massive ovarian enlargement secondary to primary hypothyroidism in a patient with a normal FSH receptor. Arch. Dis. Child. 91: 509-510 [Abstract] [Full Text]  
• Misra, A, Agrahari, D, Gupta, R (2002). Cullen's sign in amoebic liver abscess. Postgrad. Med. J. 78: 427-428 [Abstract] [Full Text]  
• Rosai, J., Marinella, M. A. (1999). Cullen's Sign in Metastatic Thyroid Cancer. NEJM 340: 1767-1768 [Full Text]