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Editorial
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Volume 340:1672-1674 May 27, 1999 Number 21
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Residual HIV-1 Disease in the Era of Highly Active Antiretroviral Therapy

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 by Zhang, L.
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 by Furtado, M. R.
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Over the past 18 years the human immunodeficiency virus type 1 (HIV-1) epidemic has evolved, with the disease shifting from a syndrome whose cause was undefined to one in which the etiologic agent of AIDS was isolated and identified, but for which therapeutic options were limited. We are now in a new era characterized by efficient therapeutic agents to combat HIV-1 in many patients. This progress has been based on the development of highly active antiretroviral therapy in which combinations of agents are given that inhibit HIV-1 replication in vivo. Although vaccines are still under development and critical issues such . . . [Full Text of this Article]

References


Related Letters:

Control of HIV despite the Discontinuation of Antiretroviral Therapy
Lisziewicz J., Rosenberg E., Lieberman J., Jessen H., Lopalco L., Siliciano R., Walker B., Lori F.
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N Engl J Med 1999; 340:1683, May 27, 1999. Correspondence

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