FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 340:1732 June 3, 1999 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Editorial by Schwartz, R. S. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

View larger version (378K): [in this window] [in a new window]   Initiation of an immune response requires an interaction between antigen-presenting cells, such as dendritic cells, and helper (CD4) T cells. Antigen-presenting cells process antigens and attract helper T cells by means of chemokines. T cells interact with antigen-presenting cells in a way that initiates a signaling cascade. A series of scanning electron micrographs shows helper T cells interacting in a tissue culture with dendritic cells. Panel A shows two small CD4 T cells (indicated in each panel by the asterisks) docking onto a large, veiled dendritic cell. Panel B shows a dendritic cell rearranging its membrane. In Panels C and . . . [Full Text of this Article]

 

This article has been cited by other articles:

• Fais, S., Malorni, W. (2003). Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions. J. Leukoc. Biol. 73: 556-563 [Abstract] [Full Text]  
• Kobayashi, M., Azuma, E., Ido, M., Hirayama, M., Jiang, Q., Iwamoto, S., Kumamoto, T., Yamamoto, H., Sakurai, M., Komada, Y. (2001). A Pivotal Role of Rho GTPase in the Regulation of Morphology and Function of Dendritic Cells. J. Immunol. 167: 3585-3591 [Abstract] [Full Text]  
• RILEY, R. L. (2001). What Nobody Needs to Know About Airborne Infection. Am. J. Respir. Crit. Care Med. 163: 7-8 [Full Text]  
• Schwartz, R. S. (1999). The New Immunology -- The End of Immunosuppressive Drug Therapy?. NEJM 340: 1754-1756 [Full Text]