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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 340:1981-1988 June 24, 1999 Number 25
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Case 19-1999— A 55-Year-Old Man with a Destructive Bone Lesion 17 Months after Liver Transplantation
Kwan Kew Lai, and Andrew E. Rosenberg

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Presentation of Case

A 55-year-old man was admitted to the hospital because of a painful right tibial lesion.

Twenty-one months before admission, the patient had undergone orthotopic liver transplantation at this hospital because of cryptogenic cirrhosis. The donor liver was fatty and suboptimal, and it was replaced with a second liver one month after the first transplantation. Insulin-dependent diabetes mellitus subsequently developed. Sixteen months before the current admission, a biopsy-confirmed acute rejection reaction was managed successfully.

Thirteen months before the current admission, the patient was readmitted to the hospital because of Enterobacter cloacae sepsis, which was thought to have originated in the urinary . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Kwan Kew Lai's Diagnosis

Pathological Discussion

Anatomical Diagnosis

References




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