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Previous Volume 340:2009 June 24, 1999 Number 25 Next

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Edited by Hans D. Ochs, C.I. Edvard Smith, and Jennifer M. Puck. 501 pp., illustrated. New York, Oxford University Press, 1999. $139.50. ISBN 0-19-510486-2.

The heroic efforts of Harvard chemist E.J. Cohn in pioneering the fractionation of albumin from plasma for delivery to the battlefields of World War II are widely known. With the end of the war these efforts were diversified, and by the late 1940s a new fraction had been prepared — the gamma globulins. Containing the antibodies for resisting disease, this fraction was soon used to confer passive immunity to measles and poliomyelitis, the two most feared viral infections of the day. The end of the war also saw the widespread introduction of antibiotics into clinical practice, and by the early . . . [Full Text of this Article]

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