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Previous Volume 340:239-240 January 21, 1999 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: An adolescent boy with Crohn's disease and enterocutaneous fistulas had a response to treatment with granulocyte colony-stimulating factor (filgrastim) after all standard treatments had failed. The patient presented at the age of eight years with swollen lips. Biopsies of the tongue and oral mucosa showed a chronic inflammatory-cell infiltrate and noncaseating granulomas — findings consistent with the presence of Crohn's disease. At the age of 14 years, rectal inflammation and a perianal fistula developed. The boy had a response to treatment with prednisolone and metronidazole, but the perianal pain recurred when the prednisolone was discontinued. He was . . . [Full Text of this Article]

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