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Worldwide, 33 million adults and 2 million children are infected with human immunodeficiency virus type 1 (HIV-1). Despite preventive efforts, the epidemic of the acquired immunodeficiency syndrome (AIDS) continues to spread rapidly. Every day 16,000 persons become infected with the virus. Most of them live in developing countries, where costly antiretroviral medications are not available. It is estimated that in 30 to 50 percent of HIV-1infected people, neurologic complications will develop. This virus can affect virtually every aspect of the central and peripheral nervous systems, directly or indirectly. The socioeconomic consequences of the neurologic dysfunction caused by HIV-1 infection are
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