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Correspondence
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Volume 340:394 February 4, 1999 Number 5
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Acute Reaction to Dipyridamole during Myocardial Scintigraphy

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To the Editor: We report an acute allergic reaction to an infusion of dipyridamole. A 56-year-old man was referred for myocardial scintigraphy. He had no history of asthma or diabetes mellitus. His medications included atenolol and gemfibrozil. He had a history of allergy to aspirin, tetracycline, and penicillin. His reactions included angioedema and dyspnea.

Dipyridamole stress testing was used because the patient had a left bundle-branch block. Approximately one minute after the infusion was started, the patient reported periorbital pruritus, but his condition was otherwise stable. The infusion was completed uneventfully with the administration of technetium-99m sestamibi at seven minutes.

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