To the Editor: We report an acute allergic reaction to an infusionof dipyridamole. A 56-year-old man was referred for myocardialscintigraphy. He had no history of asthma or diabetes mellitus.His medications included atenolol and gemfibrozil. He had ahistory of allergy to aspirin, tetracycline, and penicillin.His reactions included angioedema and dyspnea.
Dipyridamole stress testing was used because the patient hada left bundle-branch block. Approximately one minute after theinfusion was started, the patient reported periorbital pruritus,but his condition was otherwise stable. The infusion was completeduneventfully with the administration of technetium-99m sestamibiat seven minutes.
Seitz, V., Hummel, M., Marafioti, T., Anagnostopoulos, I., Assaf, C., Stein, H.
(2000). Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease. Blood
95: 3020-3024
[Abstract][Full Text]
Muschen, M., Rajewsky, K., Brauninger, A., Baur, A. S., Oudejans, J. J., Roers, A., Hansmann, M.-L., Kuppers, R.
(2000). Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma. J. Exp. Med.
191: 387-394
[Abstract][Full Text]
Hasse, U., Tinguely, M., Leibundgut, E. O., Cajot, J.-F., Garvin, A. M., Tobler, A., Borisch, B., Fey, M. F.
(1999). Clonal Loss of Heterozygosity in Microdissected Hodgkin and Reed-Sternberg Cells. JNCI J Natl Cancer Inst
91: 1581-1583
[Full Text]