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Previous Volume 340:476-480 February 11, 1999 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In his editorial¹ accompanying the reports on appetite-suppressant drugs and valvular heart disease, by Jick, Khan, and Weissman and their colleagues (Sept. 10 issue),^2,3,4 Dr. Devereux converted the "risks" reported by Jick et al.² (e.g., 7.1 per 10,000 persons) to "rates" (e.g., 0.14 per 1000 patient-years), by dividing by 50 — (10,000 patients x 5 years) ÷ 1000. The use of patient-years assumes that Jick et al. knew the actual date of onset of valvulopathy, which they did not. Without knowledge of the date of onset, the use of patient-year rates assumes that all cases of valvulopathy . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Pollick, C., Fishman, A. P. (1999). Aminorex to Fen/Phen: An Epidemic Foretold • Response. Circulation 100 : e147-e147 [Full Text]