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Previous Volume 341:765 September 2, 1999 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The definition of "chronic myeloid leukemia" (CML) in Sawyers's excellent review article (April 29 issue)¹ describes the disease as "a malignant clonal disorder of hematopoietic stem cells that results in increases in not only myeloid cells but also erythroid cells and platelets in peripheral blood and marked myeloid hyperplasia in the bone marrow." Although this definition accurately reflects the molecular and cellular pathophysiologic features of this condition, it is clinically misleading because patients with CML almost always present with an elevated granulocyte count, a variably increased platelet count (in 30 to 50 percent of patients), and anemia . . . [Full Text of this Article]

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