Humankind has been besieged through-out its evolution by microorganismsthat pose a continual challenge to the survival of the species.1Although such ancient killers as tuberculosis and malaria persistentlytake a toll of millions of lives per year, occasionally theemergence or reemergence of a microbe results in an unexpected,catastrophic pandemic with global public health consequences.As we prepare to leave the 20th century, it is worth reflectingon the fact that within the framework of an enormous but constantburden of a variety of infectious diseases, as well as a numberof mini-epidemics, this century has witnessed two . . . [Full Text of this Article]
The Origins of HIV
Scope of the Epidemic
The Successes and Limitations of Antiretroviral Therapy
Prevention of HIV Infection
Development of an HIV Vaccine
Conclusions
Source Information
From the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Address reprint requests to Dr. Fauci at the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, or at afauci@niaid.nih.gov.
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