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A correction has been published: N Engl J Med 2007;356(24):2554.

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Volume 341:1157-1158 October 7, 1999 Number 15
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Lack of Efficacy of Transdermal Nicotine in Smoking Cessation

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 by Joseph, A. M.
To the Editor: The Transdermal Nicotine in Cardiac Patients Study was a randomized, double-blind, placebo-controlled trial designed to test the safety and efficacy of transdermal nicotine as an aid in the cessation of smoking in patients with at least one type of major cardiovascular disease. A total of 584 outpatients receiving care from 10 Veterans Affairs medical centers participated in the trial. The initial report of this trial described the safety of the therapy in this high-risk outpatient population; however, 24 weeks after randomization, only 14 percent of the subjects in the nicotine-treatment group and 11 percent of those in . . . [Full Text of this Article]


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