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Previous Volume 341:1244 October 14, 1999 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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(Contemporary Cancer Research.) Edited by Anne M. Bowcock. 582 pp., illustrated. Totowa, N.J., Humana Press, 1999. $145. ISBN 0-89603-650-3.

A century ago, William Halsted introduced the radical mastectomy as a treatment for breast cancer and with it transformed breast cancer from an incurable disease to one whose course physicians could hope to alter. With the addition of radiation therapy and chemotherapy to the less disfiguring modified radical mastectomy in the mid-1970s, the treatment of breast cancer became genuinely multimodal, if nonspecific. The addition of hormonal therapies, the refinement of chemotherapeutic regimens, and the important shift toward breast-conserving surgery that followed similarly served to increase the sophistication with which this disease is approached.

Despite these advances, breast cancer has exacted . . . [Full Text of this Article]

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