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Correspondence
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Volume 341:1399-1400 October 28, 1999 Number 18
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Spinal Epidural Lipomatosis in a Patient with the Ectopic Corticotropin Syndrome

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To the Editor: Spinal epidural lipomatosis, or excess epidural fat, can compress nerve roots or the spinal cord. It occurs in patients with morbid obesity, hypothyroidism, and exogenous Cushing's syndrome1 but rarely in those with endogenous Cushing's syndrome.2,3,4 We describe a patient with spinal epidural lipomatosis who had the ectopic corticotropin syndrome.

The patient was a 36-year-old man who presented with severe back pain and weakness. He had a cushingoid appearance, weakness of his hip flexor muscles, and bandlike hyperesthesia at level T6 but no other neurologic abnormalities. His serum cortisol concentration, urinary cortisol excretion, and plasma corticotropin concentration were . . . [Full Text of this Article]

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