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Editorial
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Volume 341:1464-1465 November 4, 1999 Number 19
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Primary Angioplasty — Enduring the Test of Time

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 by Zijlstra, F.
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The role of mechanical reperfusion as compared with thrombolytic therapy for the treatment of acute myocardial infarction has remained controversial since Rentrop et al.1 first reestablished perfusion in patients with myocardial infarction by dislodging the occluding coronary thrombus with a guide wire. Since then, considerable evidence has shown that thrombolytic agents are effective in restoring blood flow, improving left ventricular function, and reducing mortality from acute myocardial infarction. Primary treatment with percutaneous transluminal coronary angioplasty has been shown to have similar benefits, and controversy continues over what method is more effective.

Those who favor thrombolytic therapy emphasize its advantages over . . . [Full Text of this Article]

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