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Correspondence
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Volume 341:1476-1477 November 4, 1999 Number 19
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Infants with CMV and HIV-1

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 by Kovacs, A.
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To the Editor: The report by Kovacs et al. (July 8 issue)1 on acceleration of human immunodeficiency virus type 1 (HIV-1) disease progression in cytomegalovirus (CMV)–infected children prompts several questions. What were the relative contributions of HIV-1 and CMV to the increased neurologic morbidity in this observational study? It is well established that both viruses may lead to impaired brain growth and progressive motor deficits. In contrast to immunocompetent infants, those who are also infected with HIV-1 may be at an increased risk for CMV encephalitis, even in the case of postnatally acquired infection, as in an infant we have . . . [Full Text of this Article]

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