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Editorial
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Volume 341:120-121 July 8, 1999 Number 2
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Cancer during Pregnancy

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 by Catlin, E. A.
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Cancer is rare during pregnancy, occurring in only about 1 per 1000 live births. More than half the cases are tumors of the uterine cervix, breast, or thyroid, which can metastasize to the placenta but not the fetus.1 Melanoma and hematologic tumors, which also can invade the placenta, may cross into the fetal circulation. In a recent review, Baergen et al.2 described 19 cases of maternal melanoma that had metastasized to the placenta. In five of these cases the tumor extended into the fetus, which died of metastatic melanoma in four of the five cases. The transmission of maternal leukemia . . . [Full Text of this Article]

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