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A correction has been published: N Engl J Med 2000;342(4):300.

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Volume 341:1697-1698 November 25, 1999 Number 22
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Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants

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 by Rothman, K. J.
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 by Tyson, J. E.
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To the Editor: The study by Tyson et al. (June 24 issue),1 while impressive in design and numbers of infants studied, does not really answer the question of whether vitamin A supplementation reduces the risk of chronic lung disease in premature infants. The main drawback of this study, as well as those published previously,2 is the definition of chronic lung disease. The best predictor of chronic lung disease is a chest x-ray film,3 whereas the authors' definition of chronic lung disease, the need for oxygen at 36 weeks' postmenstrual age, has a positive predictive value of only 63 percent.4

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