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Correspondence
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Volume 341:1701-1702 November 25, 1999 Number 22
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Musculoskeletal Tumors of Childhood

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 by Arndt, C. A.S.
To the Editor: The review by Arndt and Crist (July 29 issue)1 underplays the role of stem-cell transplantation in the treatment of Ewing's sarcoma. Our group has worked on stem-cell transplantation in Ewing's sarcoma since the early 1980s and has published data demonstrating a two-year survival rate of approximately 70 percent among patients presenting with metastasis, large lesions (those more than 8 cm), or both, at diagnosis.2 Follow-up data since 1990 show 60 percent survival at 1 to 11 years among 40 such high-risk patients. These results should be considered promising.

Several developments, however, suggest that stem-cell transplantation may become . . . [Full Text of this Article]

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