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Previous Volume 341:1702-1704 November 25, 1999 Number 22 Next

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To the Editor: Thoracic masses due to extramedullary hematopoiesis are rare, occurring most often in patients with thalassemia or congenital hemolytic anemia.¹ The masses usually cause no symptoms but can cause pleural effusion or hemothorax. Here, we describe a patient with respiratory insufficiency caused by large, hematopoietic thoracic masses.

A 51-year-old woman with type III congenital dyserythropoietic anemia² (diagnosed in 1971, with lifelong anemia) was referred to our clinic in December 1998 because of exertional dyspnea and respiratory insufficiency. In 1980, a routine radiograph of the chest had shown a small, right-sided thoracic mass; biopsy had revealed extramedullary hematopoiesis. In . . . [Full Text of this Article]

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