In this issue of the Journal, Sandler and colleagues reportthe negative results of a double-blind, placebo-controlled trialof a single intravenous dose of synthetic human secretin inchildren with autism or pervasive developmental disorder.1 Autisticdisorder is a serious neuropsychiatric disorder with onset inthe first years of life that is characterized by delayed anddeviant social and communication skills, associated with variousforms of unusual behavior (e.g., repetitive behavior and unusualresponses to the environment).2 The term pervasive developmentaldisorder not otherwise specified refers to a condition withsymptoms suggestive of autism but that does not meet the . . . [Full Text of this Article]
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Secretin Treatment for Autism
Horvath K., Rimland B., Herlihy W. C., Said S. I., Bodanszky M., Sandler A., Volkmar F.
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N Engl J Med 2000;
342:1216-1218, Apr 20, 2000.
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Horvath, K., Rimland, B., Herlihy, W. C., Said, S. I., Bodanszky, M., Sandler, A., Volkmar, F.
(2000). Secretin Treatment for Autism. NEJM
342: 1216-1218
[Full Text]