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Previous Volume 341:1937 December 16, 1999 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their report of the transfer of an aggressive natural-killer-cell lymphoma from a mother to her fetus, Catlin et al. (July 8 issue)¹ suggest that the maternal lymphoma was not rejected by the infant because of the immaturity of the fetus's lymphocytes. We suggest that a fetal antigen called HLA-G is important in protecting maternal cancer cells from rejection by the fetus.

HLA-G is selectively expressed in cytotrophoblasts, chorionic villi, amnion, and monocytes activated by interleukin-10 and interferon-.² It is a key molecule in fetal tolerance of maternal cells.³ In fact, the expression of HLA-G during . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Riteau, B., Menier, C., Khalil-Daher, I., Martinozzi, S., Pla, M., Dausset, J., Carosella, E. D., Rouas-Freiss, N. (2001). HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition. Int Immunol 13: 193-201 [Abstract] [Full Text]