To the Editor: Indirect evidence suggests that gum chewing mayhave greater metabolic effects than has been appreciated. Thethermic effect of food is reduced when nutrition bypasses themouth.1 In cows, chewing increases energy expenditure by approximately20 percent.2,3 We measured how energy expenditure changes withgum chewing in humans.
Energy expenditure was measured in a temperature-controlled,darkened, silent laboratory with an indirect calorimeter (model229, SensorMedics, Yorba Linda, Calif.) that was calibratedbefore each measurement with two primary-standard gases (a combinationof 4 percent carbon dioxide and 16 percent oxygen and a combinationof 26 percent oxygen and . . . [Full Text of this Article]
Levine, J. A.
(2004). Nonexercise activity thermogenesis (NEAT): environment and biology. Am. J. Physiol. Endocrinol. Metab.
286: E675-E685
[Abstract][Full Text]
Jessen, A. B, Toubro, S., Astrup, A.
(2003). Effect of chewing gum containing nicotine and caffeine on energy expenditure and substrate utilization in men. Am. J. Clin. Nutr.
77: 1442-1447
[Abstract][Full Text]
Levine, J., Melanson, E. L., Westerterp, K. R., Hill, J. O.
(2001). Measurement of the components of nonexercise activity thermogenesis. Am. J. Physiol. Endocrinol. Metab.
281: E670-E675
[Abstract][Full Text]
Florman, D. A., Levine, J.
(2000). More on Chewing Gum. NEJM
342: 1531-1532
[Full Text]