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Editorial
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Volume 341:193-195 July 15, 1999 Number 3
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Aortic Sclerosis — A Window to the Coronary Arteries?

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 by Otto, C. M.
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In a provocative study in this issue of the Journal, Otto and colleagues report that aortic sclerosis, a condition without obvious hemodynamic consequences, was associated with an increased risk of death from any cause and from cardiovascular causes.1 Although aortic sclerosis tended to be present in conjunction with other factors known to be associated with coronary disease and death from cardiovascular causes, the risk remained elevated after adjustment for these factors. What makes these data remarkable is the fact that this condition has been well known for decades and yet has generally been considered benign. The guidelines on valvular heart . . . [Full Text of this Article]

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