Third edition. By Alastair Compston, George Ebers, Hans Lassmann, Ian McDonald, Bryan Matthews, and Hartmut Wekerle. 592 pp., illustrated. New York, Churchill Livingstone, 1998. (Distributed by W.B. Saunders, Philadelphia.) $165. ISBN 0-443-05008-2.
Multiple sclerosis was first described about 160 years ago byJean Martin Charcot. Since then, it has become one of the mostcommon conditions faced by clinical neurologists and one ofthe most intriguing puzzles for neuroscientists. Multiple sclerosisis a relatively frequent disease in Western countries, mainlyaffecting young people and causing, in many of them, severeand irreversible disability during the 10 to 15 years afteronset. Despite its frequency, the causes and pathogenesis ofmultiple sclerosis remain uncertain, our understanding of itsnatural evolution is still in its infancy, and our ability toalter its course is . . . [Full Text of this Article]
Previous
