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Volume 341:216 July 15, 1999 Number 3

Genetics of Cerebrovascular Disease

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Edited by Mark J. Alberts. 386 pp., illustrated. Armonk, N.Y., Futura, 1999. $120. ISBN 0-87993-584-7.

Is stroke a genetic disease? Genetics of Cerebrovascular Disease puts forth the message that genetic factors do play a part in the pathogenesis of stroke. Traditionally, stroke has not been considered an inherited disease, and most cerebrovascular events are thought to be sporadic. However, there is considerable evidence supporting the view that cerebrovascular diseases are, in part, genetically determined. The chief risk factors for stroke, such as hypertension and diabetes, have a genetic component, and certain familial diseases affecting blood vessels or blood clotting are associated with an increased incidence of cerebrovascular events. The application of molecular genetic techniques to . . . [Full Text of this Article]




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