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Correspondence
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Volume 341:291-292 July 22, 1999 Number 4
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Treatment of Severe Combined Immunodeficiency

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 by Flake, A. W.
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 by Buckley, R. H.
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To the Editor: Buckley and colleagues (Feb. 18 issue)1 deserve recognition for their ongoing contribution to the treatment of patients with severe combined immunodeficiency. It is disappointing, however, that they conclude from this experience that "in utero transplantation of stem cells from related donors does not appear to offer any advantage over transplantation performed soon after birth." Since in utero transplantation was not compared with postnatal transplantation, this conclusion seems unfounded and premature.

The results of the study performed by Buckley et al. are the best that have been reported for the treatment of severe combined immunodeficiency. Even so, 22 . . . [Full Text of this Article]

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