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Previous Volume 341:375-377 July 29, 1999 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Grimbacher et al. (March 4 issue)¹ described in detail 30 patients with hyper-IgE syndrome. Recently, a 29-year-old Italian woman was admitted to our hospital because of acute back pain due to spontaneous fracture of the L3 vertebral body. She had a history of chronic generalized eczematoid lesions, diffuse microlymphadenopathy, bronchial asthma, rhinosinusal polyps, migraine-like headache, and recurrent vaginal candidiasis. During childhood, she had had frequent skin infections and recurrent pneumonitis. Additional findings included hypoplasia of the right mandibular condylus, cleft of the posterior arch of the S1 vertebra, bilateral keratoconus, ovarian and renal cysts, and fibroadenoma of . . . [Full Text of this Article]

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