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Correspondence
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Volume 341:539-540 August 12, 1999 Number 7
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Anticoagulation for Venous Thromboembolism

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 by Khamashta, M. A.
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 by Kearon, C.
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To the Editor: Kearon et al. (March 25 issue)1 tested the hypothesis that patients with a first episode of idiopathic venous thromboembolism would benefit from a course of anticoagulant therapy lasting more than three months. The authors found that patients who continued taking oral anticoagulants after receiving an initial course of treatment lasting three months had few recurrences or none, whereas those who stopped warfarin after three months had a high rate of recurrence, mainly in the first six months after the discontinuation of treatment. Unfortunately, the study did not determine whether anticoagulation reduces the risk of recurrence or simply . . . [Full Text of this Article]

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