Thyroid deficiency during the latter two thirds of gestationand the first months after delivery can result in mental retardationand sometimes neurologic deficits. Whether thyroid hormone isneeded during the first trimester is less certain. If it is,it must be supplied by the mother, because none is secretedby the fetus until the middle trimester.
During the middle and last trimesters, thyroid hormone is suppliedby both the mother and the fetus but mostly by the mother. Thisis most evident in the fate of infants with sporadic congenitalhypothyroidism. Most of these infants are normal at birth, . . . [Full Text of this Article]
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