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Figure 1. A 45-year-old man with the acquired immunodeficiency syndrome presented with night sweats, fatigue, cachexia, and a productive cough. He had a fever (temperature, 40°C), tachycardia (heart rate, 136 per minute), a leukocyte count of 2.5x103 per cubic millimeter, and hypotension (blood pressure, 90/50 mm Hg). A chest x-ray film revealed an infiltrate in the right lower lobe. A peripheral-blood smear (Wright's stain, x1000) obtained on admission showed a monocyte with a grossly distorted nucleus and numerous intracellular yeast-like organisms 2 to 4 µm in diameter with eccentric chromatin. The organisms were surrounded by an . . . [Full Text of this Article] |