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Correspondence
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Volume 342:55-58 January 6, 2000 Number 1
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Oral Antibiotics for Febrile Patients with Neutropenia Due to Cancer Chemotherapy

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 by Kern, W. V.
To the Editor: In the July 29 issue, Kern et al.1 and Freifeld et al.2 reach similar conclusions about the efficacy of oral as compared with intravenous antibiotic therapy for febrile patients with neutropenia due to cancer chemotherapy who have a low risk of complications. It is a common mistake to assume that the absence of a statistical difference between two treatments means that they are equivalent. This criticism is of particular importance in a study involving a relatively small patient population, with a low failure rate in each group.

In the study by Kern et al., the end point . . . [Full Text of this Article]

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