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Fifty years ago, in his textbook Heart Disease (4th ed. New York, Macmillan, 1951), Paul Dudley White, one of the most recognized cardiovascular physicians of his day, reflected on the progress made in cardiovascular care during the previous century and the opportunities for the next 50 years. "We must," he wrote, "and I am confident that we can, master during the next quarter century much, if not all, of the three greatest threats to the public health of this country and of much of the rest of the world . . . namely, rheumatic heart disease, high blood pressure, and
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