|
|||
| |||||||||||||||||||||||||||||||||||
A 74-year-old man was referred to the Memory and Movement Disorders Unit of this hospital because of progressive memory loss and personality changes.
The patient had been well until three years earlier, when his wife observed that he was becoming forgetful. There was subsequent progressive impairment of memory, occasional urinary incontinence, and inappropriate behavior, such as recitation of poorly constructed limericks in public. When speaking he made paraphasic errors, such as "I cannot button my tie." Although he continued to work in an intellectually demanding profession, his colleagues noted that he made many errors in judgment. Laboratory tests were negative.
Differential Diagnosis
Clinical Diagnosis
Dr. John H. Growdon's Diagnosis
Pathological Discussion
Anatomical Diagnosis
References
HOME | SUBSCRIBE | SEARCH | CURRENT ISSUE | PAST ISSUES | COLLECTIONS | PRIVACY | TERMS OF USE | HELP | beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved. |