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Previous Volume 342:1210-1211 April 20, 2000 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Acromegaly is the clinical expression of chronic secretion of excessive amounts of growth hormone. Its cardinal clinical manifestation is thickening of the skin, soft tissue, and bones of the hands and feet. It also causes thickening of these tissues throughout the body and enlargement of most viscera.

The effects of hypersecretion of growth hormone are slowly progressive. Therefore, the course of acromegaly is usually insidious, but it ultimately results in considerable disability, in addition to the often cosmetically distressing acral enlargement and the accompanying need for larger rings, gloves, and shoes. Some of the disability results from tissue overgrowth; nasopharyngeal . . . [Full Text of this Article]

References

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