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Correspondence
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Volume 342:1291-1292 April 27, 2000 Number 17
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Prevention of Sudden Death in Patients with Coronary Artery Disease

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 by Buxton, A. E.
To the Editor: Buxton et al. (Dec. 16 issue)1 report that electrophysiologically guided antiarrhythmic therapy, primarily with implantable defibrillators, but not antiarrhythmic drugs, reduces the risk of sudden death in high-risk patients with coronary disease. In Figure 1 of their article, however, the group with electrophysiologically guided therapy actually fared worse than the group with no antiarrhythmic therapy for a good part of the first year; it is only after the first year of enrollment that the two curves begin to diverge and the group receiving electrophysiologically guided therapy begins to show an advantage. No comment was made in the . . . [Full Text of this Article]

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