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Previous Volume 342:1442-1445 May 11, 2000 Number 19 Next

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In the early 1990s two randomized clinical trials showed that folic acid, or multivitamins containing folic acid, could substantially reduce a woman's risk of bearing a child with a neural-tube defect, provided that the vitamins were taken before conception.^1,2 In 1992 the Public Health Service recommended that all women of childbearing age who are capable of becoming pregnant consume 400 µg of folic acid daily.³ Not surprisingly, in a country where half the women who become pregnant each year are not planning to do so, compliance with this recommendation has been poor.⁴ At the time the recommendation was made, we . . . [Full Text of this Article]

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Fortification of Foods with Folic Acid
Lawrence J. M., Chiu V., Petitti D. B., Halliday J. L., Riley M., Kirby R. S., Flynn C., Enright H., Mills J. L.
Extract | Full Text  
N Engl J Med 2000; 343:970-972, Sep 28, 2000. Correspondence

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