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Previous Volume 342:1518-1520 May 18, 2000 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Editorial by Angell, M. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Keller, M. B. PubMed Citation

The majority of persons who have an acute episode of a major depressive disorder will have a response to the first or second treatment tried.¹ In patients with mild or moderately severe episodes, treatment with antidepressant drugs and brief psychotherapies are equally effective; in those with severe episodes, medication is usually recommended.² The treatment of chronic depression is more problematic, since in 20 to 30 percent of initial episodes, there is incomplete remission after two years.^3,4 Patients with chronic depression have marked impairments in psychosocial function, poor responses to single therapies, and very high rates of use of health care . . . [Full Text of this Article]

References

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• SCOTT, J., PALMER, S., PAYKEL, E., TEASDALE, J., HAYHURST, H. (2003). Use of cognitive therapy for relapse prevention in chronic depression: Cost-effectiveness study. Br. J. Psychiatry 182: 221-227 [Abstract] [Full Text]  
• Garland, A. (2001). Continuation phase cognitive therapy reduced relapse or recurrence in recurrent DSM-IV major depressive disorder. Evid. Based Ment. Health 4: 111-111 [Full Text]  
• FRIEDLANDER, A. H., MAHLER, M. E. (2001). Major depressive disorder: Psychopathology, medical management and dental implications. Journal of the American Dental Association 132: 629-638 [Abstract] [Full Text]  
• Scott, J. (2001). Cognitive therapy for depression. Br Med Bull 57: 101-113 [Abstract] [Full Text]  
• Angell, M. (2000). Is Academic Medicine for Sale?. NEJM 342: 1516-1518 [Full Text]