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Previous Volume 342:1675-1676 June 1, 2000 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Despite a thorough analytic effort, the work by van den Hoogen et al. (Jan. 6 issue)¹ appears methodologically flawed. As the authors state in the Methods section, blood pressure and hypertension were examined in relation to mortality from coronary heart disease after adjustment for age, total cholesterol level, and smoking status. However, the investigators neglected to address the role of diabetes mellitus as a major risk factor for coronary heart disease.

Epidemiologic research (including the pivotal Framingham Study) has shown that diabetes mellitus is a well-established factor in the pathogenesis of atherosclerosis and acts as a strong . . . [Full Text of this Article]

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