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Correspondence
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Volume 342:215-216 January 20, 2000 Number 3
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Reboxetine and Hyponatremia

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To the Editor: Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone are known side effects of selective serotonin-reuptake inhibitors such as fluoxetine and sertraline1,2 and the inhibitor of serotonin and norepinephrine reuptake venlafaxine.3 We describe the occurrence of hyponatremia in a patient treated with reboxetine, a new antidepressant drug that is a norepinephrine-reuptake inhibitor. The patient was a 72-year-old man who was hospitalized for rehabilitation for mild left hemiparesis caused by a stroke three months earlier and for treatment of severe depressive symptoms, including depressed mood, feelings of worthlessness, and recurrent thoughts of death that had begun after . . . [Full Text of this Article]

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