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A correction has been published: N Engl J Med 2000;342(13):988.

Review Article
Medical Progress
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Volume 342:334-342 February 3, 2000 Number 5
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Congenital Heart Disease in Adults— Second of Two Parts
M. Elizabeth Brickner, M.D., L. David Hillis, M.D., and Richard A. Lange, M.D.

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 by Brickner, M. E.
-PubMed Citation
Cyanotic Conditions

Patients with cyanotic congenital heart disease have arterial oxygen desaturation resulting from the shunting of systemic venous blood to the arterial circulation. The magnitude of shunting determines the severity of desaturation. Most children with cyanotic heart disease do not survive to adulthood without surgical intervention. In adults, the most common causes of cyanotic congenital heart disease are tetralogy of Fallot61 and Eisenmenger's syndrome.

Tetralogy of Fallot

Tetralogy of Fallot, the most common cyanotic congenital heart defect after infancy, is characterized by a large ventricular septal defect, an aorta that overrides the left and right ventricles, obstruction of the right ventricular outflow tract (obstruction . . . [Full Text of this Article]

Ebstein's Anomaly

Transposition of the Great Arteries

Eisenmenger's Syndrome


Source Information

From the Department of Internal Medicine, Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas.

Address reprint requests to Dr. Hillis at Rm. CS7.102, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75235-9047.

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