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Previous Volume 342:424-425 February 10, 2000 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Twenty years ago we did not have a problem with thrombophilia as a cause of venous thromboembolism in pregnant and postpartum women, or rather, we did not know we had a problem. The only known major thrombophilic disorder was deficiency of antithrombin, and it was found only rarely in such women. Recently, there has been a dramatic increase in the number of identifiable causes of thrombophilia. They include, in addition to antithrombin deficiency, protein C and protein S deficiencies, factor V Leiden, the G20210A mutation of the prothrombin gene, and homozygosity for the thermolabile variant of methylenetetrahydrofolate reductase (C677T MTHFR), . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Bates, S. M., Greer, I. A., Pabinger, I., Sofaer, S., Hirsh, J. (2008). Venous Thromboembolism, Thrombophilia, Antithrombotic Therapy, and Pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133: 844S-886S [Abstract] [Full Text]  
• The ESHRE Capri Workshop Group, (2006). Hormones and cardiovascular health in women. Hum Reprod Update 12: 483-497 [Abstract] [Full Text]  
• Bates, S. M., Greer, I. A., Hirsh, J., Ginsberg, J. S. (2004). Use of Antithrombotic Agents During Pregnancy: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126: 627S-644S [Abstract] [Full Text]  
• Donahue, B. S. (2004). Factor V Leiden and Perioperative Risk. Anesth. Analg. 98: 1623-1634 [Abstract] [Full Text]  
• Chabrier, S., Buchmuller, A. (2003). Editorial Comment--Specificities of the Neonatal Stroke. Stroke 34: 2892-2893 [Full Text]  
• (2000). Venous Thromboembolism During Pregnancy. Journal Watch Dermatology 2000: 13-13 [Full Text]  
• (2000). Familial Conditions That Increase Risk for Thrombosis During Pregnancy. JWatch Women's Health 2000: 5-5 [Full Text]  
• (2000). Venous Thromboembolism During Pregnancy. JWatch General 2000: 3-3 [Full Text]