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Volume 342:440-441 February 10, 2000 Number 6
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Virostatic Therapy for Advanced Lymphoproliferation Associated with the Epstein–Barr Virus in an HIV-Infected Patient

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To the Editor: Patients infected with the human immunodeficiency virus (HIV) are at risk for malignant non-Hodgkin's lymphoma of B-cell origin.1 We describe a patient with morphologic features of polymorphic B-cell lymphoproliferation similar to those observed after solid-organ transplantation.2

A 36-year-old homosexual man presented with dysuria, fecaluria, watery diarrhea, fever, and weight loss of 8 kg within the previous two months. HIV infection had been diagnosed in 1995. The patient had an initial CD4 T-cell count of 50 cells per microliter of blood and a viral load of 140,000 HIV copies per milliliter. He had received highly active antiretroviral therapy . . . [Full Text of this Article]

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More on Virostatic Therapy for Advanced Lymphoproliferation Associated with Epstein–Barr Virus in an HIV-Infected Patient
MacMahon E. M.E., Schmidt W., Scherübl H.
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N Engl J Med 2000; 343:71-72, Jul 6, 2000. Correspondence

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