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Correspondence
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Volume 342:659-661 March 2, 2000 Number 9
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Idiopathic Eosinophilia

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 by Bain, B. J.
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 by Simon, H.-U.
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To the Editor: Some of the cases reported by Simon et al. (Oct. 7 issue)1 as idiopathic eosinophilia could have been diagnosed as T-cell lymphoma or the Sézary syndrome from the inception. Although the authors considered a diagnosis of the Sézary syndrome in eight patients who presented with erythroderma and pruritus, they excluded that diagnosis because they did not observe the "classic" CD4+CD7–CD25– immunophenotype. Certainly, Sézary cells should express CD4; however, CD7 can be detected in patients with the Sézary syndrome,2 and some of their patients were negative for CD7 or were not analyzed for CD7. The expression of CD25 . . . [Full Text of this Article]

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