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Volume 342:666 March 2, 2000 Number 9
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Of Mice, Men, and Microbes: Hantavirus

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By David R. Harper and Andrea S. Meyer. 278 pp., illustrated. San Diego, Calif., Academic Press, 1999. $34.95. ISBN 0-12-326460-X.

In the northern part of South Korea lies the Hantaan River, and during the Korean conflict in the 1950s, 3000 United Nations troops near the river became affected with fever and myalgias associated with renal disease and ecchymoses. The disorder was initially called Korean hemorrhagic fever and was later termed hemorrhagic fever with renal syndrome. Local residents with outdoor exposure, especially those who farmed, were found to be at increased risk. Fortunately, with funding from the Department of Defense, the cause was shown in the 1960s to be a filterable agent, later called Hantaan virus — the first hantavirus.

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