Edited by D. Geraint James and Alimuddin Zumla. 616 pp., illustrated. New York, Cambridge University Press, 1999. $240. ISBN 0-521-59221-6.
The granulomatous disorders encompass a wide spectrum of commonand rare afflictions that together impose a tremendous burdenof disease. Common causes include infections such as tuberculosisand idiopathic disorders such as sarcoidosis and Crohn's disease.Undoubtedly, these latter disorders elicit interest in partbecause of their uncertain, but possibly infectious, origins.Over the past decade, use of the tools of molecular biologyhas led to major advances in our understanding of granulomatousdisorders. However, the challenge remains for the clinicianand scientist to understand the complex genetic, microbial,immunologic, and environmental factors that are responsiblefor the varied clinical . . . [Full Text of this Article]
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