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Previous Volume 343:702-709 September 7, 2000 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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A man dies because his body has rejected a heart transplant; a woman is crippled by rheumatoid arthritis; a child goes into a coma that is brought on by cerebral malaria; another child dies of an infection because of an immunodeficiency; an elderly man has advanced hepatic cirrhosis caused by iron overload. These five clinical situations are as diverse as can be, yet all have one thing in common: the cause of all of them involves the human leukocyte antigen (HLA) system, the human version of the major histocompatibility complex (MHC). Malfunction of the HLA system, which is at the . . . [Full Text of this Article]

Antigen Processing and Presentation

HLA and Selection in the Thymus

Interactions between T-Cell Receptors and Complexes of HLA Molecules and Peptides

Source Information

From the Max-Planck-Institut für Biologie, Abteilung Immungenetik, Tübingen, Germany.

Address reprint requests to Dr. Klein at the Max-Planck-Institut für Biologie, Abteilung Immungenetik, Corrensstr. 42, D-72076 Tübingen, Germany, or at jan.klein@tuebingen.mpg.de.

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