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Previous Volume 343:782-786 September 14, 2000 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Deficiencies of HLA Molecules

A clinician's attention is normally drawn to a system only when it malfunctions. The HLA system is no exception in this regard, but in contrast to other systems, it also arouses interest when it functions well — too well, in fact. The most dramatic malfunction of the HLA system occurs when its genes falter in their expression, resulting in HLA class I or class II deficiencies (the bare lymphocyte syndrome, in which "bare" refers to the low level of HLA molecules on the cell surface). Severe cases of HLA deficiencies are, in fact, not caused by defective class I or . . . [Full Text of this Article]

Abnormalities of Genes Linked to the HLA Complex

Narcolepsy

Hemochromatosis

HLA Genes and Infectious Diseases

Autoimmune Diseases

Cancer

Transplantation

Applications and Conclusions

Source Information

From the Max-Planck-Institut für Biologie, Abteilung Immungenetik, Tübingen, Germany.

Address reprint requests to Dr. Klein at the Max-Planck-Institut für Biologie, Abteilung Immungenetik, Corrensstr. 42, D-72076 Tübingen, Germany, or at jan.klein@tuebingen.mpg.de.

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