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Previous Volume 343:1041-1043 October 5, 2000 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Keller, M. B.

To the Editor: The article by Keller et al. (May 18 issue),¹ in which 29 authors contributed to a comparison of the efficacy of treatment with an antidepressant alone, psychotherapy alone, and their combination in 681 patients with chronic depression, would be expected to provide important information regarding the management of a difficult clinical problem. Unfortunately, the report has little substance and several deficiencies.

There is no control group, in spite of the authors' protestations that one is not needed, because the rate of response to placebo among patients with chronic depression is low (12 percent, according to Keller et . . . [Full Text of this Article]

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